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Table 4 Differences in breastfeeding and non-breastfeeding mothers with axSpA six months after birth

From: Axial spondyloarthritis and breastfeeding: a prospective study

 

n

Breastfeeding

N = 221

n

Non-breastfeeding

N = 95

p-value

test value

df

Age, mean (SD)

221

31.9 (4.2)

95

31.6 (3.9)

0.5

0.70

314

 Age ≥ 35 years (%)

 

63 (28.5)

 

19 (20.0)

0.1

2.50

1

 Missing

0

      

BMI (kg/m2), mean (SD)

204

25.1 (5,0)

89

27.4 (5.1)

 < 0.001

−3.75

291

 Underweight (< 18.5) (%)

 

5 (2.5)

 

0 (0.0)

0.3

  

 Normal weight (18.5–24.9) (%)

 

108 (52.9)

 

33 (37.1)

0.01

6.25

1

 Overweight (≥ 25.0) (%)

 

91 (44.6)

 

56 (62.9)

0.004

8.31

1

 Obesity (≥ 30.0) (%)

 

28 (13.7)

 

30 (33.7)

 < 0.001

15.58

1

 Missing

9

      

Tobacco a (%)

198

9 (4.5)

85

16 (18.8)

 < 0.001

15.05

1

 Missing

33

      

Educational level b

216

 

92

    

 Low (%)

 

2 (0.9)

 

2 (2.2)

0.59

  

 Intermediate (%)

 

45 (20.8)

 

39 (42.4)

 < 0.001

15.11

1

 High (%)

 

169 (78.2)

 

51 (55.4)

 < 0.001

16.44

1

 Missing

8

      

Working fulltime or part-time (%)

221

15 (6.8)

95

7 (7.4)

0.9

0.04

1

 Missing

0

      

Exercising regularly c (%)

170

113 (66.5)

77

39 (50.6)

0.02

5.61

1

 Missing

69

      

CRP mean (SD)

190

3.3 (4.3)

83

5.3 (8.6)

0.01

−2.51

271

 Missing

43

      

BASDAI mean (SD)

194

3.2 (2.3) 

79

4.1 (2.6) 

0.01

−2.731

271

 BASDAI ≥ 4 (%)

 

73 (37.6)

 

40 (50.6)

0.05

3.91

1

 Missing

43

      

ASDAS-CRP mean (SD)

145

2.1 (0.9)

64

2.6 (1.1)

 < 0.001

−3.43

207

 ASDAS-CRP ≥ 1.3 (%)

 

112 (77.2)

 

54 (84.4)

0.2

1.38

1

 Missing

107

      

VAS scores (0–100), mean (SD)

 Pain 

188

31.0 (26.3)

83

43.9 (28.9)

 < 0.001

−3.31

 

 Missing

45

      

 Fatigue 

182

37.8 (31.7)

80

46.8 (31.8)

0.03

−2.19

 

 Missing

54

      

 Total

188

32.3 (25.7)

82

45.8 (28.6)

 < 0.001

−3.54

 

 Missing

46

      

csDMARDs (%)

221

22 (10.0)

95

11 (11.6)

0.7

0.19

1

 Sulfasalazine

 

21 (9.5)

 

7 (7.4)

0.5

0.38

1

 Methotrexate

 

1 (0.5)

 

4 (4.2)

0.03

  

 Missing

0

      

TNF-inhibitors (%)

221

118 (53.4)

95

47 (49.5)

0.5

0.41

1

 Missing

0

      

Secukinumab (%)

221

1 (0.5)

95

4 (4.2)

0.03

  

 Missing

0

      
  1. n number of available data on variable, df degrees of freedom, BMI body mass index, CRP C-reactive protein, BASDAI bath ankolysing spondylitis disease activity index, ASDAS ankylosing spondylitis disease activity score, VAS visual analogue scale, csDMARDs conventional synthetic disease-modifying anti-rheumatic drugs, TNF-inhibitors tumor necrosis factor inhibitors
  2. calculated chi-square statistic, t-value, z test statistic. No test values are available where Fisher’s exact test was used
  3. asmoking and snuff use
  4. beducation level: low = elementary school, intermediate = high school/vocational education, high = college/university
  5. cat least once a month