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Table 2 Characteristics of participants at approximately 1 year postpartum based on breastfeeding practice groups

From: Relationship between breastfeeding and hepatic steatosis in women with previous gestational diabetes mellitus

 

Breastfeeding practice groupa

p-value

Group 1

Group 2

Group 3

(n = 57)

(n = 26)

(n = 47)

Clinical characteristics

    

Duration of any breastfeeding (years)

1.1 (1.0–1.2)

1.0 (1.0–1.2)

1.0 (1.0–1.1)

0.156

Current contraceptive use

   

0.602

 No or non-hormonal method

41 (71.9)

14 (53.8)

31 (66.0)

 

 Combined estrogen-progestin method

6 (10.5)

4 (15.4)

5 (10.6)

 

 Progestin-only method

10 (17.5)

8 (30.8)

11 (23.4)

 

Weight (kg)

69.1 ± 16.2

69.0 ± 11.2

59.1 ± 9.6c, d

< 0.001

BMI (kg/m2)

27.7 ± 6.0

28.0 ± 4.5

24.1 ± 3.4c, d

< 0.001

Systolic BP (mmHg)

119.0 (112.0–126.5)

126.0 (117.0–133.0)

114.0 (109.0–121.0)c, d

< 0.001

Diastolic BP (mmHg)

74.0 (67.0–82.0)

76.5 (71.0–82.3)

72.0 (66.0–79.0)

0.108

WC (cm)

90.5 ± 13.9

90.2 ± 8.7

87.8 ± 12.3c, d

< 0.001

Laboratory tests

    

FPG (mg/dL)

100.0 (90.0–106.5)

97.5 (94.0–108.3)

93.0 (87.0–101.0)c, d

0.030

HbA1c (%)

5.6 (5.3–5.9)

5.6 (5.4–5.7)

5.5 (5.2–5.8)

0.675

Fasting insulin (mU/L)

11.0 (8.4–20.9)

17.1 (9.6–23.4)

8.3 (5.3–11.8)c, d

< 0.001

Fasting C-peptide (ng/mL)

2.4 (1.9–3.2)

2.8 (2.2–3.3)

1.8 (1.5–2.3)c, d

< 0.001

HOMA-IR

2.8 (1.9–5.3)

4.3 (2.4–5.7)

1.9 (1.2–2.7)c, d

< 0.001

Cholesterol (mg/dL)

183.0 (169.0–208.0)

197.0 (176.8–228.0)

191.0 (175.0–221.0)

0.160

TG (mg/dL)

101.0 (73.0–165.5)

97.5 (83.5–167.8)

79.0 (50.0–113.0)c, d

0.009

LDL-cholesterol (mg/dL)

118.0 (109.0–147.0)

141.0 (109.3–170.5)

130.0 (114.0–152.0)

0.050

HDL-cholesterol (mg/dL)

49.0 (44.5–56.0)

50.0 (41.8–58.8)

61.0 (55.0–70.0)c, d

< 0.001

AST (U/L)

21.0 (19.0–25.5)

22.0 (18.0–27.5)

21.0 (16.0–23.0)

0.076

ALT (U/L)

17.0 (8.0–23.5)

12.5 (8.0–22.8)

12.0 (8.0–18.0)

0.462

ALP (U/L)

74.0 (59.5–84.5)

79.5 (69.0–93.3)

81.0 (63.0–97.0)

0.235

FibroScan measurements

    

CAP value (dB/m)

279.0 (191.5–324.0)

257.5 (205.3–317.3)

219.0 (189.0–271.0)c

0.034

Liver stiffness value (kPa)

4.4 (3.6–5.4)

4.6 (3.9–5.2)

4.4 (3.5–5.5)

0.803

  1. Data are presented as the mean ± SD or median (IQR) or n (%)
  2. Abbreviations: ALP alkaline phosphatase, ALT alanine transaminase, AST aspartate aminotransferase, BMI body mass index, BP blood pressure, CAP controlled attenuation parameter, EBF exclusive breastfeeding, FPG fasting plasma glucose, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, HOMA-IR homeostasis model assessment of insulin resistance, IQR interquartile range, LDL-C low-density lipoprotein cholesterol, SD standard deviation, TG triglycerides, WC waist circumference
  3. a Group 1 = breastfeeding for < 6 months; group 2 = breastfeeding for ≥ 6 months and EBF for < 6 months; and group 3 = breastfeeding for ≥ 6 months and EBF for 6 months
  4. b Differences between groups were compared using a one-way analysis of variance, Kruskal-Wallis H test, or chi-squared test
  5. cp < 0.05, compared with group 1
  6. dp < 0.05, compared with group 2