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Table 3 Hazard ratio of developing T2D in women with GDM according to duration of exclusive breastfeeding, maternal age, parity, deprivation category, BMI and family history

From: Breastfeeding frequency and incidence of type 2 diabetes among women with previous gestational diabetes compared to those without: a historical cohort study in the UK

Ā 

Univariate

Multivariate

No. (%) progressing to T2D*

Mean time to progress (months)

Hazard ratio (95% CI)

P value

Hazard ratio

P value

Latest point baby exclusively breastfeeding (total n = 1, 378)

Ā Ā Ā Ā Ā Ā 

None (n = 585)

154 (26.3)

67.6

1.44 (0.98–2.12)

0.065

1.49 (0.86–2.58)

0.151

At Birth (n = 209)

56 (26.8)

54.0

1.76 (1.13–2.74)

0.012

2.20 (1.21-4.00)

0.010

At Discharge (n = 399)

74 (18.5)

68.5

1.20 (0.79–1.83)

0.399

1.70 (0.95–3.03)

0.075

At midwife visit (n = 3)

0 (0)

0

0.0 (0.0–0.0)

0.935

0.0 (0.0–0.0)

0.958

At 2 weeks (n = 71)

26 (36.6)

73.8

1.22 (0.72–2.05)

0.459

1.81 (0.91–3.60)

0.089

At 8 weeks (n = 111)

31 (27.9)

77.6

1

Ā 

1

Ā 

Maternal age at delivery (total n = 2,458)

Ā Ā Ā Ā Ā Ā 

< 20 (n = 89)

14 (15.7)

69.5

1

Ā 

1

Ā 

20–24 (n = 278)

46 (16.5)

61.6

1.11 (0.61–2.03)

0.723

2.87 (0.39–21.15)

0.302

25–34 (n = 1322)

221 (16.7)

73.0

1.04 (0.61–1.78)

0.889

1.93 (0.27–13.96)

0.515

35 and over (n = 769)

108 (14.0)

76.2

0.95 (0.54–1.65)

0.847

1.92 (0.26–14.05)

0.520

Parity (total n = 2, 443)

Ā 

Nulliparous (n = 991)

159 (16.0)

73.0

1

Ā 

1

Ā 

Multiparous (n = 1452)

230 (15.8)

71.7

1.06(0.87–1.3)

0.548

1.03 (0.77–1.37)

0.850

SIMD quintile (n = 1, 378)

Ā Ā Ā Ā Ā Ā 

1 (most deprived, n = 385)

116 (18.6)

65.2

1.78 (1.26–2.51)

< 0.001

2.69 (1.56–4.62)

< 0.001

2 (n = 306)

80 (16.3)

70.4

1.55 (1.08–2.24)

0.017

2.36 (1.34–4.15)

0.003

3 (n = 250)

59 (15.3)

60.2

1.51 (1.03–2.23)

0.036

1.81 (1.0-3.28)

0.051

4 (n = 239)

54 (15.3)

82.0

1.18 (0.80–1.75)

0.404

1.75 (0.98–3.14)

0.061

5 (least deprived, n = 198)

46 (13.7)

98.5

1

Ā 

1

Ā 

BMI (total n = 1,686)

Ā 

Normal (210)

29 (13.8)

80

1

Ā 

1

Ā 

Overweight (332)

52 (15.7)

86.3

1.08 (0.68–1.70)

0.747

1.10 (0.65–1.85)

0.727

Obese (1135)

187 (16.5)

72.3

1.13 (0.76–1.67)

0.549

1.15 (0.73–1.79)

0.550

Family History of Diabetes (total n = 2, 484)

Ā Ā Ā Ā Ā Ā 

Yes (341)

122 (35.8)

88.4

1.88 (1.51–2.33)

< 0.001

1.77 (1.29–2.42)

< 0.001

No/Not recorded (2,143)

273 (12.7)

65.6

1

Ā 

1

Ā 
  1. *There was missing data for all variables except family history. Of the 395 who developed T2D, data on feeding were available for 341, data on maternal age and parity were available for 389, data on SIMD were available for 355, and data on BMI were available for 268