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Table 1 Demographic and clinical characteristics of women with peripartum cardiomyopathy and cardiac outcomes

From: Breastfeeding in patients with peripartum cardiomyopathy: clinical outcomes and physician counseling

 

No Lactation

Lactation

p value

(p < 0.05)

(n = 36)

(n = 18)

Age at diagnosis (yrs)

   

 Mean ± SD

31 ± 6

32 ± 6

0.56

African American Ancestry, n (%)

8 (22)

3 (17)

0.73

Hypertension (pooled), n (%)

21 (58)

5 (28)

0.12

 Pre-Existing Hypertension, n (%)

7 (19)

3 (17)

1.0

 Gestational Hypertension, n (%)

8 (22)

1 (6)

0.25

 Preeclampsia, n (%)

17 (47)

4 (22)

0.21

Gestational diabetes, n (%)

2 (6)

2 (11)

0.57

Smoking, n (%)

9 (25)

4 (22)

1.0

ACEi/ARB, n (%)*

34 (94)

14 (78)

1.0

Beta Blocker, n (%)*

32 (88)

14 (78)

1.0

Spironolactone, n (%)*

18 (50)

4 (22)

0.21

Digoxin, n (%)*

7 (19)

5 (28)

0.47

Diuretic, n (%)*†

33 (92)

12 (67)

0.20

EF at diagnosis, mean ± SD

28 ± 13

30 ± 13

0.59

EF at 12 months, mean ± SD

39 ± 16

41 ± 15

0.65

Recovered, n (%)

13 (36)

4 (22)

0.48

  1. ACEi = angiotensin-converting enzyme inhibitor; ARB = angiotensin receptor blocker; EF = ejection fraction; *Medication status known in 48 patients; †Diuretics: furosemide, bumetanide; “Recovered”: defined as EF ≥ 55%