HMHB—Pakistan | Syria [32] | India [33] | Bangladesh [34] | Pakistan [13] | Uganda, Burkina Fasso, and South Africa [35] | Kenya [29] | |
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Intervention goal | To use cognitive behavioral therapy to reduce prenatal anxiety and to facilitate participants wellbeing, social support, and bonding with their baby during pregnancy | To provide medical follow up, educate provide emotional support, check on breastfeeding, check on maternal-child relationship, discuss problems and help women who have given birth, discuss family planning | To promote exclusive breastfeeding until 6 months of age (as well as assess effects on diarrhea and child growth) | To educate and counsel mothers about exclusive breastfeeding and early initiation of breastfeeding | To use cognitive-behavioral therapy to increase the rate and duration of exclusive breastfeeding in the first six months postpartum | To determine the effect of home-based breastfeeding counselling by peer counsellors | To determine the impact of facility-based semi-intensive and home-based intensive counselling in improving exclusive breast-feeding |
Time point | Antenatal | Postnatal | Postnatal | Antenatal and postnatal | Antenatal and postnatal | Antenatal and postnatal | Antenatal and postnatal |
Frequency of delivery | Weekly for 5 visits in early to mid-pregnancy, with a 6th visit in the 3rd trimester | At least once or in a series of 4 home visits | A series of 12 monthly visits until the child reached the age of one | 15 sessions | 7 sessions | 5 sessions | 7 sessions |
Location | Health facility | Home | Home | Home | Home | Home | Home and health facility |
Delivery agent | Non-specialized providers | Trained midwives | Community health workers and nutrition workers | Peer counsellors | Community health workers | Trained peers | Trained peers |
Outcome(s) related to breastfeeding | Exclusive and recent breastfeeding both within 24 h of birth and within 24 h of an assessment at six weeks postpartum | Exclusive breastfeeding and breastfeeding practices (see below for examples) at 4 months postpartum | Primary: Exclusive breastfeeding at 3 months postpartum; Secondary: Exclusive breastfeeding at 4, 5, and 6 months of life | Prevalence of exclusive breastfeeding at 5 months postpartum and timing of initiation of breastfeeding | Rate and duration of exclusive breastfeeding at 6 months postpartum | Prevalence of exclusive breastfeeding at 12 and 24 weeks | Prevalence of exclusive breastfeeding at 6 months |
Result(s) related to breastfeeding | HMHB had a marginally significant impact on early breastfeeding i.e. in the first 24 h of life (75.4% HMHB vs. 69.0% controls; OR 1.4, 95% CI: 0.99–1.92). In unadjusted per protocol analyses, HMHB increased the odds of early (OR 1.7, 95% CI:1.2–2.6) and recent breastfeeding i.e. measured in the prior 24 h at six-weeks after birth (OR 2.1, 95% CI:1.1–4.0) | A significantly higher proportion of mothers who received four doses or one dose of the intervention, respectively, exclusively breastfed their infants (28.5% and 30%, respectively) compared to controls who received no intervention (20%), p = 0.02. However, no differences were found between these groups for other breastfeeding outcomes, e.g. breastfeeding at four months postpartum, giving fluids on the first day after birth, bottle feeding | Exclusive breastfeeding rates were significantly higher, 79% in the intervention group and 48% in the control group at 3 months (OR 4.0, 95% CI 3.0–5.4). The mean duration of exclusive breastfeeding in the intervention group was 122 days, versus 41 days in the control group | Prevalence of Exclusive breastfeeding was significantly higher at 5 months, (70%) for the intervention group and (6%) for the control group. Difference = 64%; 95% CI 57%-71%). 64% of the intervention group initiated breastfeeding in the first hour compared to 15% in the control group | At 6 months postpartum 59.6% in the intervention group and 28.6% in the control group exclusively breastfed. (Adj. HR = 0.4, 95% CI: 0.3–0.6). Prelacteal feeding was less likely among intervention mothers (Adj. RR = 0.5, 95% CI 0.3–0.8) | In Uganda, exclusive breastfeeding prevalence at 12 weeks was 82% (intervention) vs. 44% (control) (PR 1.89, 95% CI 1.70–2.11), and at 24 weeks, 59% vs. 15% (PR 3.83, 95% CI 2.97–4.95). In Burkina Faso, at 12 weeks, it was 79% vs. 35% (PR 2.29, 95% CI 1.33–3.92), and at 24 weeks, 73% vs. 22% (PR 3.33, 95% CI 1.74–6.38). In South Africa, at 12 weeks, it was 10% vs. 6% (PR 1.72, 95% CI 1.12–2.63), and at 24 weeks, 2% vs. < 1% (PR 5.70, 95% CI 1.33–24.26) | The prevalence of exclusive breastfeeding at 6 months was 23.6% in the home-based intervention group, 9.2% in the health facility-based intervention group and 5.6% in the control group. In the home-based intervention group mothers had four times increased likelihood of exclusive breastfeeding compared with controls (Adj. RR = 4·01, 95% CI: 2.30–7·01). No significant difference was found comparing exclusive breastfeeding in health- facility based intervention group and control group |