Effect of brewer’s yeast or beta-glucan on breast milk supply following preterm birth: the BLOOM study – protocol for a multicentre randomised controlled trial

Table 2 Overview of the BLOOM Study schedule of assessments

	Day 0 Baseline	Day 7 Post enrolment	Day 21 Postpartum	Infant Discharge to Home or Term Corrected Age
Questionnaires
General
- Maternal demographic & lifestyle questionnaire	X
- Postnatal health		X	X	X
Breastfeeding
- Daily breast milk diary	X	X	X
- General breast milk expression and breastfeeding questions	X	X	X	X
- Breast health questionnaire		X	X	X
- Breast Milk Expression Experience questionnaire		X		X
Mental health and wellbeing
- EPDS		X		X
- STAI-6		X		X
- PSS: NICU		X		X
- MPAS				X
Medication side-effects		X	X
Physical assessments
Maternal anthropometry		X
Maternal biospecimens*
Blood		X
Urine		X
Stool		X
Buccal swab		X
Breast milk		X
Case note audit
Pregnancy and birth history	X
Infant feeding record	X	X	X	X
Infant anthropometry	X	X	X	X
Infant morbidity and mortality				X
Protocol window	-	Day 7–9	Day 21–23	Within 3 days of event

EPDS: Edinburgh postnatal depression scale, STAI-6: Six-item State-Trait Anxiety Inventory, PSS:NICU: Parental Stressor Scale: Neonatal Intensive Care Unit, MPAS: Maternal Postnatal Attachment Scale
*All biological samples are collected for research purposes only

ISSN: 1746-4358